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General Medicine · Gastroenterology
Sample itemA man with alcoholic cirrhosis and ascites develops fever and diffuse abdominal tenderness. What is the most appropriate next step in management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Diagnostic paracentesis with ascitic fluid cell count and culture
Fever and abdominal pain in a patient with cirrhotic ascites suggest spontaneous bacterial peritonitis. It is confirmed by ascitic fluid neutrophil count, and fluid should be cultured. Diagnostic paracentesis should be done promptly in any cirrhotic patient with ascites who is ill.
Option by option
A. Increase the dose of diuretics and review in a week
More diuretic does not address infection and may precipitate kidney injury.
B. Upper gastrointestinal endoscopy
Endoscopy would look for varices or ulcers, which do not explain fever with abdominal tenderness.
C. Diagnostic paracentesis with ascitic fluid cell count and culture (correct)
Correct. Ascitic fluid analysis confirms infection and guides antibiotic therapy.
D. Plain abdominal radiograph only
A plain film cannot diagnose peritoneal infection of ascitic fluid.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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