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ENT · Nose and paranasal sinuses: superior orbital fissure syndrome
Sample itemAfter a fracture of the lateral orbital wall in a road accident, a man has ptosis, complete ophthalmoplegia, a dilated fixed pupil and numbness of the forehead. Visual acuity is normal. Which syndrome is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Superior orbital fissure syndrome
Structures passing through the superior orbital fissure, namely cranial nerves III, IV, VI and the ophthalmic division of V, are damaged, giving ophthalmoplegia, ptosis, a fixed dilated pupil and forehead anaesthesia. When the optic nerve is also involved with visual loss, it is called orbital apex syndrome.
Option by option
A. Superior orbital fissure syndrome (correct)
Correct. Nerves III, IV, VI and V1 are affected while the optic nerve is spared, with normal vision.
B. Cavernous sinus thrombosis
Cavernous sinus thrombosis is infective with fever, chemosis and bilateral progression, not post-traumatic.
C. Orbital apex syndrome
Orbital apex syndrome has the same findings plus optic nerve damage and visual loss.
D. Horner syndrome
Horner syndrome gives mild ptosis, miosis and anhidrosis, not ophthalmoplegia with a dilated pupil.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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