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ENT · Nose and paranasal sinuses: lupus vulgaris of the nose
Sample itemA young woman has a slowly enlarging reddish-brown nodule on the skin of the nasal vestibule. On pressing with a glass slide, the lesion turns an apple-jelly colour. Which organism causes this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Mycobacterium tuberculosis
Lupus vulgaris is cutaneous tuberculosis, and the nose is a favourite site. Diascopy shows the apple-jelly nodules, and untreated lesions destroy cartilage. Antitubercular therapy cures it.
Option by option
A. Rhinosporidium seeberi
Rhinosporidium seeberi forms a bleeding strawberry-like polyp with white spores, not a skin nodule.
B. Klebsiella rhinoscleromatis
Klebsiella rhinoscleromatis causes a hard, painless granulomatous nasal mass with Mikulicz cells.
C. Mycobacterium tuberculosis (correct)
Correct. Lupus vulgaris is skin tuberculosis with an apple-jelly appearance on diascopy.
D. Mycobacterium leprae
Mycobacterium leprae causes lepromatous nasal crusting and collapse with anaesthetic skin patches.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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