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ENT · Nose and paranasal sinuses: clival chordoma
Sample itemA 45-year-old has headache, diplopia from a sixth nerve palsy and nasal obstruction. CT shows a destructive midline mass of the clivus with internal calcification. Which is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Chordoma
Chordoma arises from notochord remnants along the clivus and sacrum. It is a slow-growing destructive midline tumour that presents with headache and cranial nerve palsies, notably the sixth. Angiofibroma occurs in adolescent males and arises from the sphenopalatine foramen.
Option by option
A. Craniopharyngioma
Craniopharyngioma is suprasellar and presents with visual field loss and endocrine deficits.
B. Chordoma (correct)
Correct. A destructive calcified midline clival mass with an abducens palsy fits a chordoma from notochord remnants.
C. Juvenile nasopharyngeal angiofibroma
Angiofibroma occurs in adolescent boys with epistaxis, arising from the sphenopalatine foramen.
D. Nasopharyngeal carcinoma
Nasopharyngeal carcinoma arises in the fossa of Rosenmuller and presents with a neck node or serous otitis media.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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