Nose and paranasal sinuses: Young syndrome: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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ENT · Nose and paranasal sinuses: Young syndrome

Sample item

A 32-year-old man with chronic sinusitis and bronchiectasis is infertile. Semen analysis shows azoospermia with normal testis size, sweat chloride is normal, ciliary beat is normal and the viscera are in normal position. What is the diagnosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Young syndrome

Young syndrome combines chronic sinopulmonary infection with obstructive azoospermia from inspissated epididymal secretions, with normal sweat chloride and normal cilia. Kartagener syndrome has immotile cilia and situs inversus, and cystic fibrosis gives raised sweat chloride.

Option by option

  • A. Cystic fibrosis

    Cystic fibrosis would give raised sweat chloride and congenital absence of the vas deferens.

  • B. Kartagener syndrome

    Kartagener syndrome has immotile cilia and situs inversus, which are absent here.

  • C. Young syndrome (correct)

    Correct. Obstructive azoospermia with sinopulmonary infection and normal sweat chloride and ciliary function is Young syndrome.

  • D. Klinefelter syndrome

    Klinefelter syndrome has small firm testes with raised gonadotrophins and no sinopulmonary disease.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this ENT question

What is the answer to this ENT question?

The best answer is C, Young syndrome. Young syndrome combines chronic sinopulmonary infection with obstructive azoospermia from inspissated epididymal secretions, with normal sweat chloride and normal cilia.

Why is "Cystic fibrosis" not the answer?

Cystic fibrosis would give raised sweat chloride and congenital absence of the vas deferens.

Why is "Kartagener syndrome" not the answer?

Kartagener syndrome has immotile cilia and situs inversus, which are absent here.

Why is "Klinefelter syndrome" not the answer?

Klinefelter syndrome has small firm testes with raised gonadotrophins and no sinopulmonary disease.

What concept does this question test?

It tests Nose and paranasal sinuses: Young syndrome in ENT. Kartagener syndrome has immotile cilia and situs inversus, and cystic fibrosis gives raised sweat chloride.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Nose and paranasal sinuses: Young syndrome?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.