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Ophthalmology · Neuro-ophthalmology and pupils: idiopathic orbital inflammation
Sample itemA 40-year-old has sudden painful proptosis, red eyelids and limited eye movements in one eye, without fever or sinusitis. CT shows diffuse enlargement of muscles including their tendons, and symptoms improve within 48 hours of oral prednisolone. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Idiopathic orbital inflammatory disease
Idiopathic orbital inflammation, orbital pseudotumour, presents with acute pain and a dramatic steroid response, with muscle enlargement involving the tendons. In thyroid eye disease the tendons are spared and the course is painless. Orbital cellulitis needs antibiotics and shows fever and sinus disease.
Option by option
A. Orbital cellulitis
Orbital cellulitis has fever, leucocytosis and sinus infection.
B. Carotid-cavernous fistula
A carotid-cavernous fistula gives pulsation, a bruit and dilated conjunctival vessels.
C. Thyroid eye disease
Thyroid eye disease is usually painless and spares the muscle tendons.
D. Idiopathic orbital inflammatory disease (correct)
Correct. Painful, tendon-involving enlargement with rapid steroid response is idiopathic orbital inflammation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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