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Ophthalmology · Neuro-ophthalmology and pupils: visual evoked potential
Sample itemMonths after optic neuritis, a woman's acuity is 6/6 and the disc looks normal, but she says vision remains abnormal. Which test would show a delayed P100 latency to confirm past optic nerve demyelination?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Visual evoked potential
The visual evoked potential measures conduction along the visual pathway, and demyelination delays the P100 latency even when acuity recovers. The electroretinogram records retinal activity and is normal in optic nerve disease. It is also used to assess unexplained visual loss.
Option by option
A. Electroretinogram
The ERG tests photoreceptors and bipolar cells and is normal in optic neuropathy.
B. Visual evoked potential (correct)
Correct. Prolonged P100 latency shows slow conduction in the optic nerve.
C. Fluorescein angiography
Angiography shows vascular leakage and does not measure conduction.
D. Electro-oculogram
The EOG tests the retinal pigment epithelium and photoreceptor function.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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