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Radiology · Musculoskeletal imaging: systemic sclerosis
Sample itemA woman with Raynaud phenomenon and tight skin has a hand radiograph showing resorption of the distal phalangeal tufts with soft tissue calcification. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Systemic sclerosis
Acro-osteolysis of the terminal tufts with subcutaneous calcinosis is typical of systemic sclerosis. Rheumatoid arthritis shows marginal erosions and periarticular osteopenia, gout shows punched-out erosions with overhanging edges, and osteoarthritis shows osteophytes and joint space narrowing.
Option by option
A. Systemic sclerosis (correct)
Correct. Acro-osteolysis with calcinosis points to systemic sclerosis.
B. Rheumatoid arthritis
Rheumatoid arthritis causes marginal erosions with periarticular osteopenia.
C. Osteoarthritis
Osteoarthritis causes joint space narrowing, sclerosis and osteophytes.
D. Gout
Gout causes punched-out erosions with overhanging edges.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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