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Dermatology · Papulosquamous disorders: nailfold capillaroscopy in Raynaud phenomenon
Sample itemA 35-year-old woman with cold-induced digital colour change wants to know whether it is primary or secondary Raynaud phenomenon. Which finding favours a secondary process from systemic sclerosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Dilated nailfold capillaries with areas of dropout
Abnormal nailfold capillaroscopy, with giant loops and capillary loss, together with a positive antinuclear antibody or digital ulcers, favours secondary Raynaud phenomenon. Primary disease has a normal capillary pattern and no systemic features.
Option by option
A. Dilated nailfold capillaries with areas of dropout (correct)
Correct. Enlarged capillaries and dropout suggest microvascular disease from systemic sclerosis.
B. Symmetrical attacks beginning in the teenage years
Symmetric attacks from the teens are typical of primary Raynaud.
C. Absence of digital pitting scars
Absent digital pitting scars point away from a scleroderma process.
D. Normal ESR and negative antinuclear antibody
A normal ESR with negative antinuclear antibody is more typical of primary disease.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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