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Dermatology · Papulosquamous disorders: polymorphic light eruption versus lupus
Sample itemA 28-year-old woman develops itchy papules over the exposed forearms and V of the neck a few hours after the first sunny days of spring. They settle in a week without scarring and recur each year. ANA is negative. What is the best preventive strategy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Broad-spectrum sunscreen and gradual hardening with narrowband UVB in early spring
Polymorphic light eruption is a delayed photosensitivity that recurs in spring and responds to photoprotection. Prophylactic narrowband UVB or PUVA before the season induces tolerance (hardening).
Option by option
A. Lifelong systemic steroid
Lifelong systemic steroid has unacceptable adverse effects for a benign recurring condition.
B. Oral isotretinoin
Isotretinoin treats acne and has no role in preventing light eruption.
C. Broad-spectrum sunscreen and gradual hardening with narrowband UVB in early spring (correct)
Correct. Photoprotection with prophylactic phototherapy hardens the skin.
D. Topical antifungal
A topical antifungal does not affect a photoimmunological process.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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