Pigmentary disorders: oral mini-pulse in vitiligo: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Pigmentary disorders: oral mini-pulse in vitiligo

Sample item

A 25-year-old has rapidly spreading vitiligo over the trunk and limbs, with new patches appearing every week. Which treatment can help to arrest rapid progression?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Oral mini-pulse corticosteroids on two consecutive days a week

Oral mini-pulse therapy with betamethasone or dexamethasone can stabilise rapidly progressive vitiligo. Hydroquinone or monobenzone cause depigmentation and are not stabilisers.

Option by option

  • A. Oral mini-pulse corticosteroids on two consecutive days a week (correct)

    Correct. Mini-pulse steroids arrest rapidly progressive disease.

  • B. Topical monobenzone

    Monobenzone depigments remaining normal skin in extensive disease.

  • C. Topical hydroquinone

    Topical hydroquinone lightens skin and does not halt disease.

  • D. Oral isotretinoin

    Isotretinoin is not used for vitiligo.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is A, Oral mini-pulse corticosteroids on two consecutive days a week. Oral mini-pulse therapy with betamethasone or dexamethasone can stabilise rapidly progressive vitiligo.

Why is "Topical monobenzone" not the answer?

Monobenzone depigments remaining normal skin in extensive disease.

Why is "Topical hydroquinone" not the answer?

Topical hydroquinone lightens skin and does not halt disease.

Why is "Oral isotretinoin" not the answer?

Isotretinoin is not used for vitiligo.

What concept does this question test?

It tests Pigmentary disorders: oral mini-pulse in vitiligo in Dermatology. Hydroquinone or monobenzone cause depigmentation and are not stabilisers.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Pigmentary disorders: oral mini-pulse in vitiligo?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.