Postpartum haemorrhage and emergencies: PPH drug choice: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Postpartum haemorrhage and emergencies: PPH drug choice

Sample item

A woman with severe pre-eclampsia has atonic PPH not responding to oxytocin. Which second-line uterotonic is contraindicated?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Ergometrine

Ergometrine causes vasoconstriction and a rise in blood pressure, so it is avoided in hypertension and pre-eclampsia. Carboprost, misoprostol and tranexamic acid can be used, with carboprost avoided in asthma.

Option by option

  • A. Ergometrine (correct)

    Correct. It raises blood pressure and risks stroke.

  • B. Tranexamic acid

    Tranexamic acid is an antifibrinolytic adjunct, not a vasoconstrictor.

  • C. Carboprost

    Carboprost can be used as long as there is no asthma.

  • D. Misoprostol

    Misoprostol can be used and does not raise blood pressure.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is A, Ergometrine. Ergometrine causes vasoconstriction and a rise in blood pressure, so it is avoided in hypertension and pre-eclampsia.

Why is "Tranexamic acid" not the answer?

Tranexamic acid is an antifibrinolytic adjunct, not a vasoconstrictor.

Why is "Carboprost" not the answer?

Carboprost can be used as long as there is no asthma.

Why is "Misoprostol" not the answer?

Misoprostol can be used and does not raise blood pressure.

What concept does this question test?

It tests Postpartum haemorrhage and emergencies: PPH drug choice in OBG. Carboprost, misoprostol and tranexamic acid can be used, with carboprost avoided in asthma.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Postpartum haemorrhage and emergencies: PPH drug choice?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.