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OBG · Postpartum haemorrhage and emergencies: septic abortion
Sample itemAfter an unsafe abortion a woman has fever, jaundice, haemoglobinuria and acute renal failure. Which organism is classically responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Clostridium perfringens
Clostridium perfringens produces a lecithinase that causes massive intravascular haemolysis with renal failure. Treatment is broad-spectrum antibiotics, surgical evacuation and often hysterectomy.
Option by option
A. Group B streptococcus
Group B streptococcus is a cause of neonatal sepsis.
B. Clostridium perfringens (correct)
Correct. Its toxin lyses red cells.
C. Staphylococcus epidermidis
Staphylococcus epidermidis is a skin commensal and is not the typical cause.
D. Escherichia coli
E. coli causes septic shock but not typical massive haemolysis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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