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OBG · Gynaecological endocrinology: Asherman syndrome
Sample itemA woman who had vigorous curettage after a miscarriage now has hypomenorrhoea with normal hormone levels and no withdrawal bleed after oestrogen and progestogen. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Intrauterine adhesions
Intrauterine adhesions after curettage block menstrual flow because the endometrium is destroyed, so there is no withdrawal bleed. Hysteroscopy confirms and treats them by adhesiolysis.
Option by option
A. Hyperprolactinaemia
Prolactin excess causes galactorrhoea and a hormonal pattern.
B. Premature ovarian insufficiency
Ovarian insufficiency would show raised FSH and low oestrogen.
C. Polycystic ovary syndrome
PCOS causes oligomenorrhoea with a response to progestogen.
D. Intrauterine adhesions (correct)
Correct. Scarred endometrium fails to bleed despite hormones.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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