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Radiology · Radiotherapy and nuclear medicine basics: radiotherapy for high-risk prostate cancer
Sample itemA man with locally advanced prostate cancer is treated with external beam radiotherapy. Which addition improves survival?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Androgen deprivation therapy
In locally advanced or high-risk disease, adding androgen deprivation to radiotherapy improves local control and survival. Tamoxifen, imatinib and radioiodine do not act on prostate cancer.
Option by option
A. Radioiodine
Radioiodine treats thyroid disease.
B. Androgen deprivation therapy (correct)
Correct. Androgen deprivation with radiotherapy improves survival in high-risk disease.
C. Imatinib
Imatinib targets tyrosine kinases in CML and GIST.
D. Tamoxifen
Tamoxifen is an anti-oestrogen used in breast cancer.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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