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Pathology · Vasculitis
Sample itemA 3-year-old child has had fever for six days with conjunctival injection, cracked red lips, a strawberry tongue, cervical lymphadenopathy and peeling of the fingertips. What is the most important complication to look for?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Coronary artery aneurysm
This is Kawasaki disease, a medium-vessel vasculitis of childhood. Inflammation of the coronary arteries can cause aneurysms and thrombosis, and treatment with immunoglobulin and aspirin aims to prevent this.
Option by option
A. Crescentic glomerulonephritis
Crescentic glomerulonephritis is a feature of small-vessel vasculitides, not of Kawasaki disease.
B. Intussusception
Intussusception can complicate IgA vasculitis in children but is not the key complication of Kawasaki disease.
C. Mitral stenosis
Mitral stenosis is a late result of rheumatic heart disease rather than a complication of Kawasaki disease.
D. Coronary artery aneurysm (correct)
Correct. Coronary arteritis with aneurysm formation is the main cause of morbidity.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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