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General Medicine · Respiratory medicine: acute severe asthma
Sample itemA young woman with acute severe asthma has a peak flow of 40 percent predicted and cannot complete sentences. Which combination is the appropriate initial treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Oxygen, nebulised salbutamol with ipratropium and systemic corticosteroid
Acute severe asthma requires oxygen to keep saturation 93-95 percent, repeated nebulised beta-2 agonists with ipratropium, and early systemic corticosteroid. Intravenous magnesium is added if there is poor response. Sedatives are avoided.
Option by option
A. Intravenous antibiotics and codeine
Antibiotics are not routinely required and codeine can depress respiration.
B. Oxygen, nebulised salbutamol with ipratropium and systemic corticosteroid (correct)
Correct. This is the standard first-hour package.
C. Inhaled corticosteroid alone
Inhaled steroid alone is inadequate in an acute attack.
D. Oral theophylline and bed rest
Theophylline is second line and not an initial measure.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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