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Dermatology · Papulosquamous disorders: delusional infestation
Sample itemA 60-year-old brings a matchbox of skin debris to prove he is infested with worms. Examination shows only excoriations and no parasites. Which drug class is used if he accepts treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Low-dose atypical antipsychotic such as risperidone, or pimozide
Delusional infestation, or delusional parasitosis, is a fixed false belief of infestation, often with the matchbox sign. Low-dose antipsychotics such as pimozide or newer agents like risperidone are used, with a trusting relationship. Repeated antiparasitic treatment reinforces the belief.
Option by option
A. Low-dose atypical antipsychotic such as risperidone, or pimozide (correct)
Correct. Low-dose antipsychotics are the treatment.
B. High-dose benzodiazepines
Benzodiazepines do not treat delusions.
C. Topical permethrin repeatedly
Permethrin reinforces the delusion.
D. Oral ivermectin repeated monthly
Ivermectin does not treat an absent infestation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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