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Dermatology · Hair disorders: trichorrhexis nodosa
Sample itemMicroscopy of fragile hair shafts shows nodes where the cortex splits into fibres, resembling two paintbrushes pushed together. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Trichorrhexis nodosa
Trichorrhexis nodosa is the commonest hair shaft defect, with nodes where the cortex frays, giving a paintbrush appearance and breakage. It is usually acquired from chemical or physical trauma, but it can also occur in argininosuccinic aciduria or hypothyroidism. Management is gentle hair care.
Option by option
A. Pili torti
Pili torti shows flattened hair twisted along its axis.
B. Trichorrhexis invaginata
Trichorrhexis invaginata gives bamboo hair in Netherton syndrome.
C. Monilethrix
Monilethrix shows regular beaded nodes and elliptical swellings.
D. Trichorrhexis nodosa (correct)
Correct. Paintbrush-like frayed nodes indicate trichorrhexis nodosa.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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