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Dermatology · Skin tumours: nodular melanoma
Sample itemWhich melanoma subtype has an early vertical growth phase, appears as a rapidly enlarging dome-shaped dark or pink nodule, and often has no radial growth phase?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Nodular melanoma
Nodular melanoma lacks a clear radial growth phase and enters vertical growth early, so it is often thick at diagnosis and has a worse prognosis. It may be amelanotic and mistaken for a benign lesion. The ABCDE rule often misses it, so the EFG rule (elevated, firm, growing) is used.
Option by option
A. Lentigo maligna melanoma
Lentigo maligna melanoma arises from lentigo maligna on chronically sun-damaged skin.
B. Nodular melanoma (correct)
Correct. Nodular melanoma shows early vertical growth.
C. Acral lentiginous melanoma
Acral lentiginous melanoma occurs on palms, soles and nail units.
D. Superficial spreading melanoma
Superficial spreading melanoma has a prolonged radial growth phase.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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