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Dermatology · Infections: erythema induratum of Bazin
Sample itemA 30-year-old woman has recurrent painful, deep violaceous nodules on the calves that ulcerate in cold weather. Biopsy shows lobular panniculitis with granulomas and vasculitis. Mantoux is strongly positive. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Erythema induratum of Bazin
Erythema induratum is a tuberculid, a hypersensitivity reaction to distant tuberculous antigen, and presents with calf nodules in women. It shows a lobular panniculitis with vasculitis and may ulcerate. Erythema nodosum is a septal panniculitis that does not ulcerate.
Option by option
A. Erythema nodosum
Erythema nodosum is a septal panniculitis on the shins that heals without ulceration.
B. Polyarteritis nodosa
Polyarteritis nodosa shows necrotising arteritis of medium vessels, not tuberculin positivity with granulomas.
C. Lupus vulgaris
Lupus vulgaris is a plaque of true cutaneous tuberculosis, typically on the face, with apple-jelly colour.
D. Erythema induratum of Bazin (correct)
Correct. Calf nodules with ulceration, lobular panniculitis and strong tuberculin reactivity fit this tuberculid.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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