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Dermatology · Papulosquamous: phrynoderma
Sample itemA child with chronic fat malabsorption has dry, rough, horny follicular papules on the extensor limbs and difficulty seeing in dim light. Which deficiency explains both?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Vitamin A
Phrynoderma (toad skin) is follicular hyperkeratosis from vitamin A deficiency, and night blindness reflects loss of retinal rhodopsin function. Deficiency also causes xerophthalmia and Bitot spots. Treatment is vitamin A replacement.
Option by option
A. Vitamin A (correct)
Correct. Follicular hyperkeratosis with night blindness indicates vitamin A deficiency.
B. Vitamin E
Vitamin E deficiency gives neuropathy and ataxia.
C. Vitamin C
Vitamin C deficiency gives perifollicular haemorrhage.
D. Niacin
Niacin deficiency gives pellagra.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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