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General Medicine · Renal medicine
Sample itemWhich finding most suggests a pre-renal cause of acute kidney injury in a patient with vomiting?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. History of volume loss and low blood pressure
Vomiting can cause intravascular volume depletion and reduced renal perfusion, producing pre-renal acute kidney injury that may improve after appropriate fluid replacement and treatment of the cause.
Option by option
A. Heavy proteinuria with red-cell casts
Red-cell casts suggest glomerular inflammation rather than a pre-renal state.
B. Painless gross haematuria from a stone
A stone may obstruct urine flow rather than causing a pre-renal insult.
C. History of volume loss and low blood pressure (correct)
Correct: hypovolaemia and hypotension reduce kidney perfusion.
D. Longstanding small echogenic kidneys
Small chronic kidneys suggest established chronic kidney disease.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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