Renal medicine: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Renal medicine

Sample item

Which finding is most concerning for acute kidney injury?

AStable serial creatinine values with preserved urine outputBIsolated microscopic haematuria with unchanged filtrationCDistal sensory loss from chronic peripheral neuropathyDA rising serum creatinine from baseline

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. A rising serum creatinine from baseline

A rise in serum creatinine from baseline indicates a fall in kidney filtration and should prompt assessment of cause, severity, and complications.

Option by option

A. Stable serial creatinine values with preserved urine output
Stable serial creatinine with preserved output does not indicate an acute fall in filtration.
B. Isolated microscopic haematuria with unchanged filtration
Microscopic haematuria needs evaluation but does not by itself establish acute kidney injury.
C. Distal sensory loss from chronic peripheral neuropathy
Peripheral neuropathy does not measure glomerular filtration or renal perfusion.
D. A rising serum creatinine from baseline (correct)
Correct: rising creatinine indicates reduced kidney function.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is D, A rising serum creatinine from baseline. A rise in serum creatinine from baseline indicates a fall in kidney filtration and should prompt assessment of cause, severity, and complications.

Why is "Stable serial creatinine values with preserved urine output" not the answer?

Stable serial creatinine with preserved output does not indicate an acute fall in filtration.

Why is "Isolated microscopic haematuria with unchanged filtration" not the answer?

Microscopic haematuria needs evaluation but does not by itself establish acute kidney injury.

Why is "Distal sensory loss from chronic peripheral neuropathy" not the answer?

Peripheral neuropathy does not measure glomerular filtration or renal perfusion.

What concept does this question test?

It tests Renal medicine in General Medicine. The correct option holds because: Correct: rising creatinine indicates reduced kidney function.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Renal medicine?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.