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Pathology · Chronic inflammation
Sample itemWhich cell type is central to chronic inflammation and tissue repair signaling?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Macrophage
Macrophages persist in chronic inflammation, remove debris, present antigen, release cytokines and growth factors, and can promote either ongoing injury or fibrosis depending on the surrounding signals.
Option by option
A. Osteoclast only
Osteoclasts resorb bone and are not general chronic inflammation regulators.
B. Platelet only
Platelets contribute to haemostasis but are not the central chronic inflammatory cell.
C. Macrophage (correct)
Correct: macrophages orchestrate chronic inflammatory and repair responses.
D. Erythrocyte
Erythrocytes transport oxygen but do not direct chronic inflammation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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