Granulomatous inflammation: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Pathology · Granulomatous inflammation

Sample item

What is the defining cellular arrangement in a granuloma?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Aggregates of activated macrophages with epithelioid appearance

Granulomas are organized collections of activated macrophages, often with epithelioid morphology and giant cells, formed when the immune system attempts to contain persistent organisms or foreign material.

Option by option

  • A. Clusters of adipocytes around nerves

    Adipocytes around nerves do not define granulomatous inflammation.

  • B. Diffuse acellular collagen only

    Collagen may accompany chronic disease but does not itself define a granuloma.

  • C. Sheets of mature erythrocytes

    Erythrocytes are circulating red cells and do not form granulomas.

  • D. Aggregates of activated macrophages with epithelioid appearance (correct)

    Correct: activated macrophages are the structural core of granulomas.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is D, Aggregates of activated macrophages with epithelioid appearance. Granulomas are organized collections of activated macrophages, often with epithelioid morphology and giant cells, formed when the immune system attempts to contain persistent organisms or foreign material.

Why is "Clusters of adipocytes around nerves" not the answer?

Adipocytes around nerves do not define granulomatous inflammation.

Why is "Diffuse acellular collagen only" not the answer?

Collagen may accompany chronic disease but does not itself define a granuloma.

Why is "Sheets of mature erythrocytes" not the answer?

Erythrocytes are circulating red cells and do not form granulomas.

What concept does this question test?

It tests Granulomatous inflammation in Pathology. The correct option holds because: Correct: activated macrophages are the structural core of granulomas.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Granulomatous inflammation?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.