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Microbiology · Mycology
Sample itemWhich opportunistic fungus is especially associated with invasive lung disease and characteristic septate branching hyphae in profoundly neutropenic patients?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Aspergillus fumigatus
Aspergillus fumigatus can invade lung tissue and blood vessels in severely immunocompromised patients; microscopy classically shows septate hyphae with acute-angle branching.
Option by option
A. Trichophyton rubrum
Trichophyton is a dermatophyte affecting keratinized tissue.
B. Candida albicans
Candida more often causes mucosal or bloodstream yeast infection.
C. Cryptococcus neoformans
Cryptococcus is an encapsulated yeast with a different clinical syndrome.
D. Aspergillus fumigatus (correct)
Correct: Aspergillus has septate acute-angle branching hyphae.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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