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General Medicine · Infectious diseases: HIV
Sample itemWhich infection is particularly associated with advanced HIV when the CD4 count is below 200 cells/mm3?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Pneumocystis jirovecii pneumonia
Pneumocystis jirovecii pneumonia is an important opportunistic infection in advanced HIV, classically at low CD4 counts. It often presents with subacute dyspnea, dry cough, fever, and hypoxemia.
Option by option
A. Streptococcal pharyngitis
Streptococcal pharyngitis is common but not a defining advanced-HIV opportunistic illness.
B. Uncomplicated influenza
Influenza can affect anyone and is not the classic CD4-threshold opportunistic infection.
C. Pneumocystis jirovecii pneumonia (correct)
Correct. PCP risk rises substantially as CD4 count falls below about 200 cells/mm3.
D. Acute otitis externa
Otitis externa is not the classic low-CD4 opportunistic infection in this context.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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