Cell adaptation: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Pathology · Cell adaptation

Sample item

What cellular adaptation explains increased left-ventricular wall thickness in chronic hypertension?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Hypertrophy

Hypertrophy is enlargement of existing cells in response to increased workload; cardiac myocytes enlarge because they have limited proliferative capacity.

Option by option

  • A. Ischaemia

    Ischaemia is reduced tissue blood flow.

  • B. Hyperplasia

    Hyperplasia is increased cell number.

  • C. Metaplasia

    Metaplasia changes differentiated cell type.

  • D. Hypertrophy (correct)

    Correct: increased cardiomyocyte size thickens the ventricular wall.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is D, Hypertrophy. Hypertrophy is enlargement of existing cells in response to increased workload; cardiac myocytes enlarge because they have limited proliferative capacity.

Why is "Ischaemia" not the answer?

Ischaemia is reduced tissue blood flow.

Why is "Hyperplasia" not the answer?

Hyperplasia is increased cell number.

Why is "Metaplasia" not the answer?

Metaplasia changes differentiated cell type.

What concept does this question test?

It tests Cell adaptation in Pathology. The correct option holds because: Correct: increased cardiomyocyte size thickens the ventricular wall.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Cell adaptation?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.