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Pathology · Acute inflammation
Sample itemWhat is the main vascular effect of histamine?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Vasodilation and increased permeability
Histamine rapidly increases vascular permeability and causes vasodilation, allowing plasma proteins and leukocytes to enter inflamed tissue.
Option by option
A. Red-cell production
Erythropoiesis is marrow function.
B. Arterial thrombosis only
Thrombosis is not its main direct action.
C. Fibroblast collagen synthesis
Fibroblasts synthesize collagen later in repair.
D. Vasodilation and increased permeability (correct)
Correct: histamine drives early vascular inflammation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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