Neoplasia: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Neoplasia

Sample item

What does anaplasia indicate in a tumour?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Poor differentiation and loss of normal cellular features

Anaplasia refers to lack of differentiation with pleomorphism, hyperchromasia, and abnormal mitoses, features associated with aggressive malignant behaviour.

Option by option

  • A. Benign encapsulation

    Encapsulation may occur in benign lesions.

  • B. Complete tumour regression

    Regression is not anaplasia.

  • C. Normal tissue repair

    Repair is not neoplastic differentiation.

  • D. Poor differentiation and loss of normal cellular features (correct)

    Correct: poor differentiation is anaplasia.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is D, Poor differentiation and loss of normal cellular features. Anaplasia refers to lack of differentiation with pleomorphism, hyperchromasia, and abnormal mitoses, features associated with aggressive malignant behaviour.

Why is "Benign encapsulation" not the answer?

Encapsulation may occur in benign lesions.

Why is "Complete tumour regression" not the answer?

Regression is not anaplasia.

Why is "Normal tissue repair" not the answer?

Repair is not neoplastic differentiation.

What concept does this question test?

It tests Neoplasia in Pathology. The correct option holds because: Correct: poor differentiation is anaplasia.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Neoplasia?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.