Neoplasia: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Neoplasia

Sample item

A 62-year-old woman with weight loss and early satiety has a firm 2 cm nodule at the umbilicus, and biopsy shows adenocarcinoma. What is the eponym for this finding?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Sister Mary Joseph nodule

A Sister Mary Joseph nodule is a metastasis in the umbilicus from an intra-abdominal or pelvic adenocarcinoma, such as stomach or ovary. It signals advanced disease.

Option by option

  • A. Virchow node

    Virchow node is a left supraclavicular node, reached by the thoracic duct.

  • B. Sister Mary Joseph nodule (correct)

    Correct. An umbilical metastasis is the Sister Mary Joseph nodule.

  • C. Krukenberg tumour

    Krukenberg tumour is an ovarian metastasis with signet ring cells.

  • D. Blumer shelf

    Blumer shelf is a rectal pouch deposit felt on rectal examination.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is B, Sister Mary Joseph nodule. A Sister Mary Joseph nodule is a metastasis in the umbilicus from an intra-abdominal or pelvic adenocarcinoma, such as stomach or ovary.

Why is "Virchow node" not the answer?

Virchow node is a left supraclavicular node, reached by the thoracic duct.

Why is "Krukenberg tumour" not the answer?

Krukenberg tumour is an ovarian metastasis with signet ring cells.

Why is "Blumer shelf" not the answer?

Blumer shelf is a rectal pouch deposit felt on rectal examination.

What concept does this question test?

It tests Neoplasia in Pathology. It signals advanced disease.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Neoplasia?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.