Renal pathology: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Renal pathology

Sample item

What mechanism causes post-renal acute kidney injury?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Urinary outflow obstruction

Post-renal kidney injury results when obstruction raises tubular and Bowman-space pressure, reducing glomerular filtration until relieved.

Option by option

  • A. Reduced cardiac output only

    Low output is a pre-renal cause.

  • B. Autoimmune podocyte injury

    Podocyte injury causes nephrotic syndrome.

  • C. Urinary outflow obstruction (correct)

    Correct: obstruction directly reduces filtration.

  • D. Excess erythropoietin

    Erythropoietin does not obstruct urine flow.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Urinary outflow obstruction. Post-renal kidney injury results when obstruction raises tubular and Bowman-space pressure, reducing glomerular filtration until relieved.

Why is "Reduced cardiac output only" not the answer?

Low output is a pre-renal cause.

Why is "Autoimmune podocyte injury" not the answer?

Podocyte injury causes nephrotic syndrome.

Why is "Excess erythropoietin" not the answer?

Erythropoietin does not obstruct urine flow.

What concept does this question test?

It tests Renal pathology in Pathology. The correct option holds because: Correct: obstruction directly reduces filtration.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Renal pathology?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.