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Pathology · Hepatic pathology
Sample itemWhat is the common mechanism of alcoholic steatosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Increased hepatic triglyceride accumulation
Alcohol metabolism alters hepatic redox state and lipid handling, promoting triglyceride accumulation within hepatocytes and fatty liver.
Option by option
A. Loss of all hepatocyte glycogen
Glycogen loss is not the main mechanism.
B. Excess collagen cross-linking only
Fibrosis develops later but is not initial steatosis.
C. Immune destruction of bile ducts only
Bile-duct destruction is a different pathology.
D. Increased hepatic triglyceride accumulation (correct)
Correct: altered lipid metabolism produces steatosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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