Gastrointestinal pathology: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Gastrointestinal pathology

Sample item

What is the defining lesion in ulcerative colitis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Continuous mucosal colonic inflammation beginning at rectum

Ulcerative colitis causes continuous mucosal inflammation beginning in the rectum and extending proximally to variable extent within the colon.

Option by option

  • A. Gastric ulcer from Helicobacter only

    H. pylori causes peptic disease.

  • B. Diverticula in sigmoid colon

    Diverticula are structural outpouchings.

  • C. Continuous mucosal colonic inflammation beginning at rectum (correct)

    Correct: continuous rectal-based mucosal disease is typical.

  • D. Transmural skip lesions anywhere in gut

    Skip transmural disease is Crohn disease.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Continuous mucosal colonic inflammation beginning at rectum. Ulcerative colitis causes continuous mucosal inflammation beginning in the rectum and extending proximally to variable extent within the colon.

Why is "Gastric ulcer from Helicobacter only" not the answer?

H. pylori causes peptic disease.

Why is "Diverticula in sigmoid colon" not the answer?

Diverticula are structural outpouchings.

Why is "Transmural skip lesions anywhere in gut" not the answer?

Skip transmural disease is Crohn disease.

What concept does this question test?

It tests Gastrointestinal pathology in Pathology. The correct option holds because: Correct: continuous rectal-based mucosal disease is typical.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastrointestinal pathology?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.