Laboratory pathology: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Laboratory pathology

Sample item

Why is immunohistochemistry used on tumour tissue?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Identify lineage and protein expression to refine diagnosis

Immunohistochemistry detects specific antigens in tissue sections, helping determine tumour lineage, receptor status, and differential diagnosis alongside morphology.

Option by option

  • A. Culture live bacteria from fixed tissue

    Fixed tissue is not cultured for live bacteria.

  • B. Measure arterial blood gas directly

    Blood gases use fresh blood analysis.

  • C. Identify lineage and protein expression to refine diagnosis (correct)

    Correct: antigen staining refines pathological classification.

  • D. Replace microscopic morphology entirely

    Morphology remains essential.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Identify lineage and protein expression to refine diagnosis. Immunohistochemistry detects specific antigens in tissue sections, helping determine tumour lineage, receptor status, and differential diagnosis alongside morphology.

Why is "Culture live bacteria from fixed tissue" not the answer?

Fixed tissue is not cultured for live bacteria.

Why is "Measure arterial blood gas directly" not the answer?

Blood gases use fresh blood analysis.

Why is "Replace microscopic morphology entirely" not the answer?

Morphology remains essential.

What concept does this question test?

It tests Laboratory pathology in Pathology. The correct option holds because: Correct: antigen staining refines pathological classification.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Laboratory pathology?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.