Gastroenterology: inflammatory bowel disease: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Gastroenterology: inflammatory bowel disease

Sample item

Which feature favors Crohn disease over ulcerative colitis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Transmural inflammation with skip lesions

Crohn disease can involve any gastrointestinal segment in discontinuous transmural lesions, leading to strictures, fistulas, and perianal disease. Ulcerative colitis typically causes continuous mucosal colitis starting at the rectum.

Option by option

  • A. Transmural inflammation with skip lesions (correct)

    Correct. Skip lesions and transmural disease are defining Crohn patterns.

  • B. Toxic megacolon never occurs

    Toxic megacolon can occur in severe colitis, including Crohn colitis.

  • C. Continuous rectal involvement only

    Continuous rectal involvement is typical of ulcerative colitis.

  • D. Disease confined to mucosa

    Mucosa-limited disease favors ulcerative colitis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Medicine questions

Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is A, Transmural inflammation with skip lesions. Crohn disease can involve any gastrointestinal segment in discontinuous transmural lesions, leading to strictures, fistulas, and perianal disease.

Why is "Toxic megacolon never occurs" not the answer?

Toxic megacolon can occur in severe colitis, including Crohn colitis.

Why is "Continuous rectal involvement only" not the answer?

Continuous rectal involvement is typical of ulcerative colitis.

Why is "Disease confined to mucosa" not the answer?

Mucosa-limited disease favors ulcerative colitis.

What concept does this question test?

It tests Gastroenterology: inflammatory bowel disease in General Medicine. Ulcerative colitis typically causes continuous mucosal colitis starting at the rectum.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastroenterology: inflammatory bowel disease?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.