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General Medicine · Endocrinology: acromegaly
Sample itemA patient has enlarged hands, coarse facial features, headaches, glucose intolerance, and bitemporal visual-field loss. What diagnosis is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Acromegaly from pituitary adenoma
Acromegaly results from excess growth hormone after epiphyseal closure, usually due to a pituitary adenoma. A macroadenoma can compress the optic chiasm and cause bitemporal hemianopia.
Option by option
A. Addison disease
Addison disease causes cortisol deficiency and hyperpigmentation.
B. Primary hypothyroidism
Hypothyroidism causes fatigue, weight gain, and cold intolerance.
C. Pheochromocytoma
Pheochromocytoma causes episodic catecholamine symptoms.
D. Acromegaly from pituitary adenoma (correct)
Correct. Somatic overgrowth and chiasmal compression point to pituitary GH excess.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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