Cell adaptation: hypertrophy: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Cell adaptation: hypertrophy

Sample item

Which example best illustrates physiologic hypertrophy?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Increase in uterine smooth-muscle mass during pregnancy

Hypertrophy is an increase in cell size, often in tissues with limited cell division. Pregnancy causes physiologic smooth-muscle hypertrophy and hyperplasia of the uterus.

Option by option

  • A. Barrett esophagus from reflux

    Barrett esophagus is metaplasia.

  • B. Squamous metaplasia in smokers

    Smoking-related bronchial change is metaplasia.

  • C. Increase in uterine smooth-muscle mass during pregnancy (correct)

    Correct. Pregnancy produces an adaptive increase in uterine muscle mass.

  • D. Endometrial dysplasia

    Dysplasia is disordered cellular growth.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Increase in uterine smooth-muscle mass during pregnancy. Hypertrophy is an increase in cell size, often in tissues with limited cell division.

Why is "Barrett esophagus from reflux" not the answer?

Barrett esophagus is metaplasia.

Why is "Squamous metaplasia in smokers" not the answer?

Smoking-related bronchial change is metaplasia.

Why is "Endometrial dysplasia" not the answer?

Dysplasia is disordered cellular growth.

What concept does this question test?

It tests Cell adaptation: hypertrophy in Pathology. Pregnancy causes physiologic smooth-muscle hypertrophy and hyperplasia of the uterus.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Cell adaptation: hypertrophy?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.