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General Medicine · Cardiology: mitral stenosis
Sample itemA 34-year-old woman with a history of rheumatic fever has exertional breathlessness. She has a loud first heart sound, an opening snap and a mid-diastolic rumble at the apex. Echocardiography shows a mitral valve area of 0.9 cm2 with pliable, mobile leaflets, minimal subvalvular fusion, mild mitral regurgitation and no left atrial thrombus. What is the most appropriate intervention?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Percutaneous balloon mitral valvotomy
Symptomatic severe mitral stenosis (valve area 1.5 cm2 or less) needs relief of the mechanical obstruction. When the leaflets are pliable, there is little calcification or subvalvular disease, regurgitation is no more than mild and the left atrium is free of thrombus, percutaneous balloon valvotomy gives excellent results. Replacement is reserved for unfavourable anatomy.
Option by option
A. Percutaneous balloon mitral valvotomy (correct)
Balloon valvotomy splits the fused commissures and is the preferred first procedure in this favourable valve morphology.
B. Open surgical mitral commissurotomy after a trial of ACE inhibitors
ACE inhibitors do not relieve a fixed mechanical obstruction, and surgical commissurotomy is only chosen when balloon valvotomy is unsuitable.
C. Mitral valve replacement with a mechanical prosthesis
Valve replacement carries operative risk and lifelong anticoagulation, and is reserved for calcified, rigid valves or significant regurgitation.
D. Lifelong diuretics and digoxin without intervention
Drugs control heart rate and congestion but leave the fixed obstruction untouched, so symptoms and pulmonary hypertension progress.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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