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Dermatology · STI: chlamydia in pregnancy
Sample itemA woman at 20 weeks of pregnancy has chlamydial cervicitis. Which drug is preferred?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Azithromycin 1 g as a single dose
Azithromycin as a single 1 g dose is the preferred treatment for chlamydia in pregnancy. Tetracyclines are avoided because of dental staining and bone effects on the fetus, and fluoroquinolones are not advised in pregnancy.
Option by option
A. Azithromycin 1 g as a single dose (correct)
Correct. Single-dose azithromycin is preferred in pregnancy.
B. Ciprofloxacin 500 mg twice daily
Ciprofloxacin is avoided in pregnancy and is not a chlamydia regimen.
C. Tetracycline 500 mg four times daily
Tetracycline is contraindicated in pregnancy for the same reasons as doxycycline.
D. Doxycycline 100 mg twice daily for 7 days
Doxycycline is contraindicated in pregnancy.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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