Try it
Pathology · Inflammation and repair: exuberant granulation tissue
Sample itemA chronic leg wound has a raised, beefy-red, friable mass of granulation tissue projecting above the level of the surrounding skin and preventing the edges from epithelialising. What is this called?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Exuberant granulation tissue
Excessive granulation tissue protrudes above the wound surface and blocks migration of epithelium, delaying healing. It is treated by cautery or excision so that re-epithelialisation can occur. A keloid and a hypertrophic scar are excessive collagen deposits in a scar after healing, not granulation tissue.
Option by option
A. Exuberant granulation tissue (correct)
Correct. Overgrown granulation tissue blocks epithelial migration and must be removed.
B. Keloid
A keloid is a scar of excess collagen that grows beyond the wound margins.
C. Hypertrophic scar
A hypertrophic scar is excess collagen confined to the original wound.
D. Desmoid tumour
A desmoid tumour is a fibromatosis that infiltrates deep tissues and is not granulation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Pathology questions
- HaematopathologyBinucleate 'owl-eye' cells that stain for CD15 and CD30 are characteristic of which cond…
- NeuropathologyEosinophilic intracytoplasmic inclusions in the pigmented neurons of the substantia nigr…
- HaemodynamicsWhich of the following is NOT a component of Virchow's triad for thrombosis?
- Granulomatous diseaseNon-caseating granulomas with Schaumann bodies and asteroid bodies are typical of: