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Radiology · Neuroimaging: pilocytic astrocytoma
Sample itemAn 8-year-old with an unsteady gait has a large cerebellar hemispheric cystic mass on MRI containing an avidly enhancing mural nodule. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Pilocytic astrocytoma
The cyst with a mural nodule is the classic pattern for pilocytic astrocytoma, a WHO grade 1 tumour with an excellent prognosis after complete resection. Haemangioblastoma gives a similar appearance but arises in adults, often with von Hippel-Lindau disease.
Option by option
A. Ependymoma
Ependymoma lies in the fourth ventricle with calcification and extension through the foramina.
B. Medulloblastoma
Medulloblastoma is a solid, midline vermian mass with restricted diffusion.
C. Haemangioblastoma
Haemangioblastoma mimics the picture but occurs in adults and is linked to von Hippel-Lindau disease.
D. Pilocytic astrocytoma (correct)
Correct. A paediatric cerebellar cyst with an enhancing nodule is typical.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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