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Radiology · Neuroimaging: dysembryoplastic neuroepithelial tumour
Sample itemA 10-year-old has had drug-resistant focal seizures since early childhood. MRI shows a wedge-shaped cortical lesion in the temporal lobe with a multicystic T2 appearance, no surrounding oedema, no mass effect and little or no enhancement. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Dysembryoplastic neuroepithelial tumour
DNET is a benign cortical glioneuronal tumour of children and young adults presenting with refractory seizures. It is stable over years, lacks oedema and is cured by resection of the lesion.
Option by option
A. Oligodendroglioma
Oligodendroglioma occurs in adults, mostly frontal, with dense calcification.
B. Glioblastoma
Glioblastoma enhances irregularly with necrosis and extensive oedema in older adults.
C. Meningioma
A meningioma is extra-axial with a dural base and homogeneous enhancement.
D. Dysembryoplastic neuroepithelial tumour (correct)
Correct. A cortical multicystic lesion with no oedema in a child with refractory seizures fits DNET.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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