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Radiology · Neuroimaging: tuberculoma
Sample itemA child from an endemic area has seizures and a single ring-enhancing parenchymal lesion with a relatively T2-hypointense centre. MR spectroscopy shows a lipid-lactate peak. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Tuberculoma
A caseating granuloma has solid central caseation that is dark on T2, with a lipid peak on spectroscopy. A cysticercus cyst shows an eccentric scolex and a pyogenic abscess has a bright cavity with restricted diffusion.
Option by option
A. Glioblastoma
Glioblastoma is an irregular thick-walled necrotic mass with extensive oedema in adults.
B. Tuberculoma (correct)
Correct. A T2-dark centre with a lipid peak points to a tuberculoma.
C. Neurocysticercosis in the colloidal vesicular stage
Neurocysticercosis shows an eccentric dot (scolex) within a cyst, with a smaller lesion size.
D. Pyogenic abscess
A pyogenic abscess has a T2-bright liquid centre with markedly restricted diffusion.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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