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Radiology · Neuroimaging: lacunar infarct
Sample itemA hypertensive diabetic man has pure motor hemiparesis. MRI shows a 10 mm diffusion-restricting lesion in the posterior limb of the internal capsule. Which vascular pathology underlies this infarct?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Lipohyalinosis of small penetrating arteries
Lacunes are small deep infarcts in the basal ganglia, internal capsule, thalamus and pons, from disease of single penetrating arteries. Hypertension and diabetes cause lipohyalinosis and microatheroma in these vessels.
Option by option
A. Haemodynamic watershed failure
Watershed infarcts lie between territories at the cortical border zones.
B. Lipohyalinosis of small penetrating arteries (correct)
Correct. Penetrating artery disease from hypertension and diabetes causes lacunar infarcts.
C. Cardioembolism from atrial fibrillation
Cardioembolism usually causes larger cortical or wedge-shaped infarcts.
D. Atherothrombosis of the internal carotid artery
Large artery atherothrombosis produces larger territorial or artery-to-artery embolic infarcts.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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