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Dermatology · Viral infections: erythema infectiosum
Sample itemA child with bright red cheeks followed by a lacy reticular rash on the limbs has a sibling with hereditary spherocytosis. Which complication is that sibling at risk of?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Transient aplastic crisis
Parvovirus B19 infects erythroid progenitors and halts red cell production. In chronic haemolytic anaemias such as sickle cell disease or spherocytosis, this causes a transient aplastic crisis.
Option by option
A. Haemolytic uraemic syndrome
Haemolytic uraemic syndrome is linked to Shiga toxin E. coli.
B. Transient aplastic crisis (correct)
Correct. Erythroid arrest in shortened red cell survival leads to aplastic crisis.
C. Encephalitis
Encephalitis is not a typical complication of B19.
D. Myocarditis
Myocarditis is typically caused by enteroviruses.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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