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Dermatology · Viral infections: roseola infantum
Sample itemA 14-month-old has three days of high fever, after which the fever abruptly settles and a pink maculopapular rash appears on the trunk. Which virus is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Human herpesvirus 6
Roseola infantum (exanthem subitum) is caused by HHV-6, and sometimes HHV-7. The rash appears as the fever subsides, and febrile seizures are a recognised complication.
Option by option
A. Human herpesvirus 6 (correct)
Correct. Rash after defervescence is the hallmark of HHV-6.
B. Coxsackievirus
Coxsackievirus produces oral and acral vesicles.
C. Rubella virus
Rubella has rash with mild fever and postauricular nodes.
D. Parvovirus B19
Parvovirus B19 produces slapped cheeks with a lacy rash.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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