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Dermatology · Viral infections: Gianotti-Crosti syndrome
Sample itemA child has symmetric, monomorphic, skin-coloured papules over the cheeks, buttocks and extensor limbs, sparing the trunk. With which virus was this condition first described?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Hepatitis B virus
Gianotti-Crosti syndrome, or papular acrodermatitis, was first described with hepatitis B infection. It is self-limited over weeks and can be triggered by other viruses such as EBV.
Option by option
A. Human papillomavirus
HPV causes warts.
B. Rubella virus
Rubella causes a generalised macular rash instead.
C. Hepatitis B virus (correct)
Correct. Hepatitis B was the original association.
D. Hepatitis C virus
Hepatitis C is not the classic association.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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