Try it
Dermatology · Skin tumours: Marjolin ulcer
Sample itemA non-healing, everted-edge ulcer develops in a 30-year-old burn scar on the leg. Which malignancy is it most likely to be?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Squamous cell carcinoma
A Marjolin ulcer is a squamous cell carcinoma arising in chronic scars, burns or sinuses. It tends to be aggressive and can metastasise to regional nodes.
Option by option
A. Malignant melanoma
Melanoma arises from melanocytes and is pigmented.
B. Squamous cell carcinoma (correct)
Correct. Chronic scars transform into squamous cell carcinoma.
C. Basal cell carcinoma
BCC arises on sun-exposed hair-bearing skin and rarely in scars.
D. Dermatofibrosarcoma protuberans
DFSP presents as an indurated plaque, not an ulcer in a burn scar.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Dermatology questions
- Blistering disordersA patient has flaccid blisters that rupture easily and a positive Nikolsky sign. Which c…
- LeprosyIn which type of leprosy is the lepromin test strongly positive?
- Pigmentary disordersA man has well-demarcated chalk-white macules on his hands and around his mouth. A skin…
- Drug reactionsWhich of the following drugs is a well-recognised trigger of Stevens–Johnson syndrome an…